EtEraser ™ SE Ikuramo rya Endotoxin

EtEraser ™ SE Ikuramo rya Endotoxin

1. Amakuru y'ibicuruzwa

Lipopolysaccharide (LPS) ni endotoxine ya bagiteri kandi ni ingenzi cyane y'urukuta rw'utugingo ngengabuzima twa bagiteri.Recombinant proteinfrom E.coli mubisanzwe irimo urwego rwo hejuru rwa endotoxine.Gukuraho ayaendotoxine birakenewe cyane mubikorwa byo hasi.

EtEraser SE Endotoxin Gukuramo ibikoreshobyashizweho kugirango bikureho endotoxine yanduye mubisubizo byamazi.Ibikoresho birimo kontinendotoxin ikuraho resin ihuza kugabanya urugero rwa endotoxine mu ngero za poroteyine ≥99% mu gihe kitarenze amasaha 2.

Ibikoresho birimo inkingi ya endotoxine yabanje gupakirwa inkingi ya miriyoni 1.5, Buffer ya Equilibration, Buffer ya Regeneration Buffer hamwe na pyrogen-freecollection tube hamwe ninama.Inkingi ifite ubushobozi buke bwo guhuza> 2000, 000 EU / ml.Iki gicuruzwa gishobora gukoreshwa inshuro zigera kuri eshanu niba cyarakozwe neza.Ubusabane bwa resin buraboneka muburyo bworoshye kandi bushobora kuba up-scalingin biopharmaceutical process.

EtEraser SE Endotoxin Gukuramo ibikoreshoikoresha urwego rwibiryo rwahinduweε-poly-L-lysineashigh affinity ligand kuri endotoxine.Ibisigarira ni amasaro ya agarose ahamye cyane kandi nta ngaruka za cytotoxique ku mubiri w'umuntu.Nyuma yo kwezwa, ntagisigara cyuburozi cyagumye murugero.Ibiibikoresho bya endotoxincanbe ikoreshwa mumiti ya poroteyine, inkingo, antibodies, ADN / RNA, polysaccharide nibindi byitegererezo byibinyabuzima.

2. Ibiranga ibicuruzwa

• gutuza cyane - ntabwo bigira ingaruka kubikorwa bya sample ya bibiologiya

• ubushobozi bwo guhuza cyane -> 2000000 EU / ml

• idafite uburozi —–> Ibiribwa bidafite uburozi ligands, nta cytotoxiceffects poly lysine

• kugarura poroteyine nyinshi -> 95% kugarura poroteyine kuri poroteyine

• gukuraho cyane - gukuraho> 99% endotoxine, urwego rwa endotoxine murugero rushobora kuba munsi ya 0.1 EU / ml nyuma yimikorere ya endotoxinremoving

• uburyo bunini bwo gukoresha - burashobora gukoreshwa mugukuraho poroteyine, peptide, antibodies, inkingo, polysaccharide nizindi ngero za biologiya;